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Eicosapentaenoic acid membrane incorporation impairs cholesterol efflux from cholesterol-loaded human macrophages by decreasing the cholesteryl ester mobilization from lipid droplets.

David Kessler described improved interaction in between the FDA plus the drug business on what facts needs to be A part of NDAs as a crucial advantage of PDUFA. He said, "By way of example, in fiscal calendar year 1993, 34 of the new programs that came in the FDA were sent back to the business mainly because they had been inadequately organized or lacking crucial details.

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Atorvastatin lowers the expression of prostaglandin E2 receptors in human carotid atherosclerotic plaques and monocytic cells: likely implications for plaque stabilization.

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